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The full list of biochemical compromises can only be speculated due to the ability of carbidopa and benserazide to induce hundreds of intertwined peripheral and central PLP function collapses, many of which may not be fully understood at present.
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Sporadic cases of a symptom complex resembling neuroleptic malignant syndrome (NMS) have been reported in association with dose reductions or withdrawal of certain antiparkinsonian agents such as levodopa, carbidopa levodopa, or carbidopa levodopa extended release.
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By strict criteria, movements that are precipitated by respiratory disturbances (such as apnea) should not be scored, and movements in this setting should not be considered periodic leg movement disorder.
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These same adverse reactions may also occur when Carbidopa Tablets are administered with these products.
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Carbidopa inhibits peripheral decarboxylation of levodopa, thus increasing availability of levodopa for distribution into the CNS.
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The Drug-Nutrient Interactions table may not include every possible interaction.
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