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Could you elaborate on the dosages of taurine per day used in this study and recommendations for practitioners?
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PNAC has been variously defined, but the diagnosis essentially requires an elevation in conjugated bilirubin (CB) in patients receiving PN, in the absence of an alternative cause for hyperbilirubinemia.
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Full institutional review board approval was obtained from each participating institution, and informed written consent was obtained from the parents or legal guardian of every subject enrolled.
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Unless there is a specific cause for concern regarding the adequacy of taurine provision, the clinician probably does not need to routinely assess serum taurine levels in the neonate receiving taurine-supplemented PN.
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The regression model also included subject effects, however, we do not present the results for the subject effects.
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Laboratory tests including serum alkaline phosphatase, cholesterol, aspartate, and alanine aminotransferase were measured monthly, and results of these tests showed no change during the treatment periods in all groups ().
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